Systems Biology and Human Metabolism
Systems Biology and Systems Medicine arethe new branches of science, investigating cell as a whole with the help of biological data and computational methods rather than focusing solely on individual cellular components and providing solutions to biomedical problems. Transcriptomics, proteomics and metabolomics, high-throughput measurement of the messenger RNA, proteins and metabolites respectively, constitute the basis of the systems biology and enable scientists to understand the complexities occurring in cells simultaneously. One of the important research area in systems biology is human metabolism, which covers all the chemical reactions existing in the human body. Our aim is to investigate metabolic changes occurring in human tissues due to perturbations by employing the Systems Biology and Systems Medicine approaches.
Researchers: Mustafa Sertbaş, Elif Esvap, Şafak Kılıç, Selma Başıbüyük, Handan Çetin
PhD and Master thesis will be offered to graduate students who have strong computational background and interest in genome scale modeling/quantitative methods.